With recurring zigzags, spirals, and other simple geometric patterns, ancient rock art is sometimes surprisingly similar across the globe. One hypothesis is that the artists were all using psychoactive compounds, which nudged the brain toward certain patterns. Now, a new find from a roughly 500-year-old cave used by Native Americans suggests such compounds may indeed have been an important component of their rock art. But the art itself may not have depicted the experience of tripping.

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